Cart
sales@molnova.com
Chelidonic acid
CAS No. 99-32-1
Chelidonic acid( Jerva acid | Jervaic acid | γ-Pyrone-26-dicarboxylic acid )
Catalog No. M20309 CAS No. 99-32-1
Chelidonic acid is a component of Chelidonium majus L. used as a mild analgesic an antimicrobial?an acentral nervous system sedative. Chelidonic acid also shows anti-inflammatory activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 30 | In Stock |
|
| 100MG | 43 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameChelidonic acid
-
NoteResearch use only, not for human use.
-
Brief DescriptionChelidonic acid is a component of Chelidonium majus L. used as a mild analgesic an antimicrobial?an acentral nervous system sedative. Chelidonic acid also shows anti-inflammatory activity.
-
DescriptionChelidonic acid is a component of Chelidonium majus L. used as a mild analgesic an antimicrobial?an acentral nervous system sedative. Chelidonic acid also shows anti-inflammatory activity.
-
In VitroChelidonic acid dose-dependently decreases IL-6 production at 0.1-10 μM, inhibits expression of IL-6 mRNA at 1-10 μM.Chelidonic acid (0.1-10 μM) decreases caspase-1 activation, nuclear NF-κB activation, and increases cytosol NF-κB activation.Chelidonic acid is a glutamate decarboxylase inhibitor, with a Ki of 1.2 μM. Chelidonic acid does not promote formation of apoenzyme or react with free pyridoxal-P.
-
In VivoChelidonic acid (0.2, 2 mg/kg p.o.) attenuates allergic reaction induced by ovalbumin in mice.
-
SynonymsJerva acid | Jervaic acid | γ-Pyrone-26-dicarboxylic acid
-
PathwayApoptosis
-
TargetCaspase
-
RecptorCaspase-1|NF-κB
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number99-32-1
-
Formula Weight184.1
-
Molecular FormulaC7H4O6
-
Purity>98% (HPLC)
-
SolubilityDMSO:4 mg/mL (21.72 mM)
-
SMILESOC(=O)c1cc(=O)cc(o1)C(O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Singh D K Gulati K Ray A . Effects of chelidonic acid a secondary plant metabolite on mast cell degranulation and adaptive immunity in rats[J]. International Immunopharmacology 2016 40:229-234.
molnova catalog
related products
-
Fmoc-Val-Ala-PAB
Fmoc-Val-Ala-PAB is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery.
-
Raptinal
Raptinal activates caspase-3 directly and initiates intrinsic caspase-dependent apoptosis pathway in multiple cell lines.
-
Lucidenic acid B
Lucidenic acid B (Lucidenicacid B), a natural compound extracted from Ganoderma lucidum, induces activation of caspase-9 and caspase-3 and cleavage of PARP, which can induce apoptosis in human leukemia cells through mitochondrial mediation.
